DR. RAMEY NOTES: Zebras are among the toughest and meanest animals out there. I recall working on one at the Houston Zoo a number of years back. It had a hoof abscess that would have crippled a horse. The poor thing was barely limping. Their temperament is also likely the reason why they’ve never been successfully domesticated – if they could have been domesticated, they certainly would have been domesticated (like most other equids).